Tag Archive for: Bio4Energy Biopolymers and Biochemical Conversion Technologies

Overlay to medical dressing made from woody nanofibre networks. Nanofibre base gel in left-bottom corner. Images by courtesy of Linn Berglund. Collage by Anna Strom.

New Stride in Wound Healing Expected, as Researchers Add New Material for Medical Dressings

On the back of successfully introducing sea kelp as a base material for hydrogels used in wound healing—and selling the rights to Norwegian firm Alginor ASA—Bio4Energy researchers are back with a deep-dive into making medical dressings for complex or chronic wounds. This time, the base material will be made from woody residues from trees.

Linn Berglund of Luleå University of Technology received a grant from national trade union Swedish Forest Industries, official voice of the sector, to place woody residues as the base material of choice in the treatment of wounds that require a certain level moisture to heal, but need to be rid of excess liquid formed at various stages of the healing process.

Based on a series of pre-studies, she will be using nanotechnology to make networks of wood fibres that hold just the right amount of moisture at the base of the dressing, which will have a transparent overlay.

“We are moving one step closer to the perfect wound dressing. We already have promising results with dressings that take up a lot of excess liquid in moist environments”.

“We are moving one step closer [to the perfect wound dressing]. We already have promising results with dressings that take up a lot of excess liquid in moist environments”, according to Berglund, researcher and long-standing member of Bio4Energy’s team of experts at nanotechnology.

“When it comes to burns for example, the liquid should be transported away, not closed in”, she added.

The efficacy of the nanofibre network, together with the transparent top part, should allow for the healing to be monitored without the need for frequent changes of the dressing.

“The transparency of the material creates unique possibilities”, Berglund told Bio4Energy Communications.

The project will run at least until the end of next year. By that time, the researchers expect to know more about the way in which the dressing materials react at various degrees of swelling due to liquid retention. We are talking about characterisation down to nano scale.

“We are going to use atomic force microscopy [coupled with] trials enabled by new equipment for rheology measurements”.

Atomic Force Microscopy is a very-high-resolution type of scanning probe technique, with resolutions in the order of fractions of a nanometre, according to Wikipedia. 

Other legs of the set up include life cycle assessment studies to check the environmental impacts; not only of the wound dressing at the end of life, but also of the production. Moreover expensive chemicals are used in the production. The researchers are going to look for ways to reduce the chemical input while obtaining similar results.

The grant is part of a Young Researchers Award, awarded in spring of this year, with funding from a Gunnar Sundblad Foundation.

For more information

Young Researchers Award (Page in Swedish)

Swedish Forest Industries

Contact

Linn Berglund, Bio4Energy Biopolymers and Biochemical Conversion Technologies

Related News

Breakthrough Innovation: Hydrogels from Norwegian Kelp to Be Commercialised – Bio4Energy

Related projects

Relation of wood structure and chemistry to nanocellulose extraction and properties – Bio4Energy

Utilising the natural composition of industrial bio-based residues for efficient separation of functional nanofibers – Bio4Energy

Bio4Enery Going Strong: New Scientists, Collaborations

Bio4Energy scientists and advanced students met at Umeå, Sweden, ready to form new research collaborations. 

Bio4Energy’s most recent platform leaderNils Skoglund, opened up for collaboration with Environment and Nutrient Recycling; and with his team presenting new lines of research.

New Bio4Energy researchers, bringing the membership count to 225, took the stage; pitching and matching.

The research environment is stronger than ever, taking its collaborations, as well as own education and training to new levels.

Moreover, expect news in terms of Bio4Energy’s outreach and online presence to follow in the third or fourth quarter of this year.

Quinoa Project Classifies New Building Block for Biorefinery

A long-running research project designed to create the conditions for making renewable fuels, chemicals and pesticides from residues of the agricultural crop quinoa; grown in extreme environments; has hit a major milestone.

Bio4Energy’s long-running ‘Quinoa Project’, started in 2017 by scientists in Sweden and Bolivia, not only has expanded to a multi-partner effort, but also has classified and provided a detailed map of characteristics of a previously unknown bacterium that can be at the base of high value-added biorefinery products.

This bacterium lives on the Andean Altiplano, or high-altitude plateau, of the great mountain range straddling Bolivia and a number of other South American countries. To protect itself from the intense sunlight and high salt concentration of its environment, it produces a type of polymer (a base component of many living organisms), which the scientists believe can be at the base of a number of high value-added biorefinery applications. It is this “exopolysaccharide” polymer that can become products for everyday use down the line.

“We believe that this type of polymer will be useful for producing products of high market value. We can think about applications such as fine chemicals, medical materials and food additives”, said Carlos Martín Medina, Umeå University; who shares the project leadership with Cristhian Carrasco of the Bolivian Universidad Mayor de San Andrés.

This means that scientists across the world who have the competence and access to infrastructure, with the classification of this bacterium, Bacillus atrophaeus, have the possibility to use the new research results for making bio-based applications from crops grown in extreme environments.

In Bolivia and other South American countries, a good part of the population are farmers who rely on the production of the protein-rich staple crop quinoa for subsistence.

One the one hand, demand for this health food from the rest of the world has dwindled as importers such as the U.S.A. have turned to growing the crop domestically. On the other, important negative environmental consequences have sprung from the quinoa production, including depleted and contaminated soils, due to monoculture and use of fossil resource-based fertilizers, as well as a problematic amount of agricultural waste.

Several of the governments of South America see great promise in biorefinery. This means the production of fuels, chemicals and materials; using renewable starting materials such as organic waste, instead of fossil resources such as oil or gas.

However, methods and tools for converting agricultural residue, such as quinoa stalks, must be invented. Given the harsh environment of the high Altiplano—a salt flat situated at an altitude of 3000 – 4500 metre above sea level—the size of the task is great.

In a next step, researchers at Umeå University, Sweden will investigate which industries may benefit most from the present discovery. In other words, use applications will be identified.

The present project is a collaboration between scientists at Umeå University, Bolivian Universidad Mayor de San Andrés of Bolivia and consultant researchers at the RISE Research Institutes of Sweden.

The overall Quinoa Project enjoys backing from the Swedish Research Council, Bio4Energy and the Swedish International Development Agency.

Scientific article

The collaboration partners have described the identification, isolation and characterisation of the new bacterial strain in the following scientific article; Chambi D, Lundqvist J, Nygren E, Romero-Soto L, Marin K, Gorzsás A, Hedenström M, Carlborg M, Broström M, Sundman O, Carrasco C, Jönsson LJ, Martín C. 2022. Production of Exopolysaccharides by Cultivation of Halotolerant Bacillus atrophaeus BU4 in Glucose- and Xylose-Based Synthetic Media and in Hydrolysates of Quinoa StalksFermentation 8(2):79.